On behalf of the Department of Neurosurgery, Ain Shams University, Cairo; we would like to express our pleasure and honor to invite you to the Second Middle Eastern Society of Stereotactic and Functional Neurosurgery (MSSFN) congress in Cairo, 6th to 8th February 2019. The marvelous success of the First congress of our society held in Dubai, Jan. 2016 made a big step in the awareness and practice of stereotactic and functional neurosurgery in our region.